Clinical Genomics

Transforming Patient Care with Genomic Intelligence

At Alstronix Technologies, our Clinical Genomics services bridge the gap between advanced genomic sequencing and real-world healthcare. We empower hospitals, diagnostics labs, and clinicians to integrate genome-driven insights into diagnosis, treatment, and disease prevention.

Our platform combines Rapid Whole Genome Sequencing (rWGS) with AI-powered variant interpretation — tailored for the genetic diversity of the Indian population — to support faster, more accurate clinical decision-making.

 What We Offer

·       End-to-End Genomic Testing Workflow

·       Sample processing and sequencing (via partner labs)

·       Bioinformatics pipeline

·       Clinical-grade variant classification (ACMG/AMP guidelines)

·       Custom gene panels and phenotype-based filtering

AI-Augmented Variant Interpretation

Our machine learning models prioritize variants based on:

·       Clinical databases (ClinVar, OMIM, HGMD)

·       Patient phenotype integration (HPO terms)

·       Disease-gene relationships and conservation scores

·       Indian population allele frequencies for local relevance

 Customizable Clinical Reports

·       Tiered variant classification (Pathogenic, Likely Pathogenic, VUS, etc.)

·       Gene-disease match summaries

·       Visualization of impacted regions (optional)

·       Designed for geneticists, clinicians, and patients alike

Areas of Focus

·       Rare Genetic Disorders

·       Neurogenetics

·       Cardiogenomics

·       Newborn & Pediatric Genetic Screening

·       Carrier Screening & Prenatal Genomics

Technologies Used

·       rWGS & rWES: For broad and deep genetic coverage

·       GATK, DeepVariant, BWA, SAMtools: High-fidelity variant calling

·       VEP, ANNOVAR, ClinVar, gnomAD: Functional and clinical annotations

·       AI Engines: Pathogenicity prediction and variant prioritization

Who We Work With

·       Multispecialty Hospitals

·       Genetic Counselling Centres

·       Clinical Diagnostic Labs

·       Paediatric & Rare Disease Clinics

·       Oncologists and Cardiologists

 Outcomes We Deliver

·       Faster time-to-diagnosis for genetic conditions

·       Evidence-based treatment options

·       Risk profiling for hereditary disorders

·       Improved patient and family counselling

Partner With Us for Clinical Genomics

We offer flexible engagement models — whether you’re looking to integrate genomic services into your hospital, outsource your bioinformatics pipeline, or co-develop specialized diagnostic panels.