Population Genomics

Mapping India's Genetic Diversity, Enabling the Future of Precision Health

India is home to one of the most genetically diverse populations in the world. At Alstronix Technologies, we’ve developed a specialized Population Genetics Platform to decode this diversity—empowering researchers, clinicians, and policymakers to make more informed decisions in public health, diagnostics, and genomics research.

What Is the Population Genetics Platform?

It is a genomic research and analytics infrastructure designed to:

·       Analyze and compare genomic data across Indian subpopulations· 

·       Discover region-specific variants and ancestry components

·       Support large-scale population genomics initiatives

·   Integrate findings into clinical applications like PGx and rare disease screening

Core Features

 Ancestry & Admixture Analysis

·       Identify ancestry components such as ASI, ANI, Steppe, IVC, and Iranian Farmer

·       Trace migration routes and admixture patterns

·       Compare populations within and beyond the Indian subcontinent

 Variant Frequency Databases

·       Build regional allele frequency maps

·       Identify founder mutations and rare variants

·       Support diagnostics with population-specific references

 Clustering & Gene Pool Definition

·       Use PCA, ADMIXTURE, FST, and hierarchical clustering

·       Reveal hidden structure within populations

·       Define micro and macro gene pools for research and healthcare use

Visualization & Insights Dashboard

·       Interactive maps and graphs

·       Subpopulation comparisons

·       Genotype-phenotype correlations

·       Custom dashboards for research and institutional projects

 Use Cases

·        Clinical Genomics: Improve diagnostic accuracy by filtering variants against local populations

·        Research: Investigate human history, migration, and disease susceptibility

·        Pharma: Stratify trial populations and identify genomic biomarkers

·        Public Health: Inform newborn screening and carrier testing programs

Collaboration Ready

We work with:

·       Academic researchers

·       Genomics startups

·       Government genome initiatives

·       International consortiums

·       Diagnostic labs and hospitals

Our platform is designed to scale from a small study to national biobank-level datasets.

Built for India, Aligned with Global Standards

Our platform aligns with FAIR data principles, uses standardized pipelines (GATK, ADMIXTURE, PLINK, etc.), and supports export-ready results for publications and global collaborations.

Let’s Understand Our DNA—Together

We believe that unlocking India’s population genetics is key to the future of personalized healthcare and scientific discovery.